Brochure: General MLPA Information

MLPA is the go-to technique for studying gene copy number variations (CNVs) associated with disease. With MLPA’s optimized multiplex PCR-based method, it is possible to detect deletions and duplications in up to 60 DNA sequences in one easy reaction, without PCR primer bias. In addition, MLPA’s detection range stretches from complete chromosomes down to single exons, and the method is so sensitive that it can reliably discriminate genes from highly similar pseudogenes. This is why laboratories worldwide rely on MLPA for studying genetic disorders and tumours.

This brochure provides an overview of the MLPA and MS-MLPA techniques and some of their most popular applications. More detailed information about MS-MLPA can be found in this brochure. More information about our products can be found in one of our application-specific brochures, via our assay finder, or in our full price list.