MRC stands for Microbiology Research Centre.
MRC-Holland bv is a follow-up of Microbiology Research Centre Holland, founded in 1985 by Dr. Jan Schouten. Originally the main products produced by MRC-Holland were restriction endonucleases–purified from a wide range of bacteria and blue green algae–and DNA molecular weight markers. These products were sold in bulk amounts to distributing companies worldwide until 2000.
In 1997, MRC-Holland started focusing on developing new techniques for DNA analysis including Multiplex Ligation-dependent Probe Amplification, or MLPA®. The MLPA technology was first described in Nucleic Acids Research 30, e57 (2002) by Schouten et al. Hundreds of MLPA probe sets have now been developed for a wide variety of genes and applications, including many rare applications.
At present, all activities of MRC-Holland are directed to the production of new MLPA-based products and the development of novel MLPA-based techniques.